作者机构:
[李衡峰; 贺国文; 朱耀东; 陈俊] School of Materials Science and Engineering, Central South University, Changsha , China;[朱耀东; 贺国文] College of Chemical and Environmental Engineering, Hunan City University, Yiyang , China
通讯机构:
[Li, H.-F.] S;School of Materials Science and Engineering, Central South University, Changsha, China
期刊:
Journal of Fluorine Chemistry,2014年161:1-10 ISSN:0022-1139
通讯作者:
Yang, Xiaoping
作者机构:
[Yang, Xiaoping] Hunan City Univ, Coll Chem & Environm Engn, Yiyang 413000, Hunan, Peoples R China.;[Guan, Aiying] Shenyang Res Inst Chem Ind, State Key Lab Discovery & Dev Novel Pesticide, Shenyang, Peoples R China.;[Yang, Xiaoping] Hunan City Univ, Coll Chem & Environm Engn, Yingbin Rd 518, Yiyang 413000, Hunan, Peoples R China.
通讯机构:
[Yang, Xiaoping] H;Hunan City Univ, Coll Chem & Environm Engn, Yingbin Rd 518, Yiyang 413000, Hunan, Peoples R China.
关键词:
Androgen receptor;Fluorine-containing small molecule;Non-steroidal antiandrogen;Prostate cancer
摘要:
Prostate cancer is one of leading causes of male deaths in Europe and US and is becoming a dramatically increasing malignancy in Asian countries including China. This disease is related to hormone malfunction linked with androgen receptor cell signaling. Targeting androgen receptor has been a major strategy for treating this disease. Among these treatments, small molecules such as flutamide, bicalutamide and newly FDA-approved MDV3100 are the mainstay of drugs in clinical use. Interestingly, all of them are fluorine-containing compounds, indicating a unique role of fluorine atom on treating this cancer. In this mini-review, we summarize the prostate cancer-related cell signaling, chemistry and mechanisms of action of these drugs, highlighting the importance of fluorine chemistry on treating prostate cancer. (C) 2014 Elsevier B.V. All rights reserved.
作者机构:
[章毅; Zeng, Guang-Ming; 李贞; 汤琳; 刘灿; 陈耀宁; 庞娅; 黎媛萍] College of Environmental Science and Engineering, Hunan University, Changsha 410082, China;[章毅; Zeng, Guang-Ming; 李贞; 汤琳; 刘灿; 陈耀宁; 庞娅; 黎媛萍] Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha 410082, China;[黎媛萍] College of Chemistry and Environmental Engineering, Hunan City University, Yiyang 413000, China
通讯机构:
College of Environmental Science and Engineering, Hunan University, China
作者机构:
[Fang Yue-cheng; He Guo-wen; Li Heng-feng; Li Jun] Cent South Univ, Sch Mat Sci & Engn, Changsha 410083, Hunan, Peoples R China.;[He Guo-wen] Hunan City Univ, Coll Chem & Environm Engn, Yiyang 413000, Peoples R China.
通讯机构:
[Li Heng-feng] C;Cent South Univ, Sch Mat Sci & Engn, Changsha 410083, Hunan, Peoples R China.
期刊:
Applied Mechanics and Materials,2013年252:228-231 ISSN:1660-9336
通讯作者:
Xiao, G.(xiaoguqing@yahoo.com.cn)
作者机构:
[Guqing Xiao; Peng Tang] College of Chemistry and Environmental Engineering, Hunan City University, Yiyang 413000, China
通讯机构:
[Xiao, G.] C;College of Chemistry and Environmental Engineering, , Yiyang 413000, China
会议名称:
International Conference on Applied Mechanics and Manufacturing System (AMMS 2012)
会议时间:
NOV 24-25, 2012
会议地点:
Guangzhou, PEOPLES R CHINA
会议论文集名称:
Applied Mechanics and Materials
关键词:
Adsorption;Hyper-cross-linked resin;Phenol
摘要:
A hyper-cross-linked polymeric adsorbent GQ-1 functionalized with acetamino groups and hydroxyl groups was synthesized to remove phenol. Results showed that the maximum adsorption capacity of GQ-1 emerged at the molecular state of phenol. More favorable adsorption of phenol onto GQ-1 than XAD-4 was further demonstrated by thermodynamic analysis. The breakthrough capacity of GQ-1 was 2.53 times that of XAD-4 when the effluent concentration reached 5mg/L.
期刊:
Journal of Chemical and Pharmaceutical Research,2013年5(12):782-788 ISSN:0975-7384
通讯作者:
Song, J.
作者机构:
[Song, Juanjuan] School of Chemical and Environmental Engineering, Hunan City University, Yiyang, Hunan, China
摘要:
Taking water system of limestone-gypsum Wet Flue Gas Desulfurization (WFGD) device as object of study. First, this paper carries on the analysis to the quality of desulfurization wastewater, then in view of the water quality characteristic of desulfurization wastewater the paper proposes the materialized treatment method, and conducts the experimental study. In the materialized method selecting polymeric aluminum ferric silicate sulfate (PAFSS) as the coagulant, then using the orthogonal experiments determine PAFS best text condition under remove of the sulfide, the fluoride and the COD by PAFSS: the pH value 8~9,PAFSS throwing content 20ml/l, PAM throwing content 10ml/l, coagulation mixing time 25min, settling time 20min. Under the best test condition the treatment effect: after coagulation processing, sulfide elimination rate 99.3%; fluoride elimination rate 96.5%;COD elimination rate 78.5%. And the results achieve requests of GB 8978-1998 integrated wastewater discharge standard.
摘要:
A series of polyimide composites with various mass fractions of multi-walled carbon nanotubes (MWNTs) were prepared by in situ polymerization. To increase the chemical compatibility of carbon nanotubes with the polyimide matrix, MWNTs were treated with an acid mixture and sulfoxide chloride in turn. The modified MWNTs are dispersed homogeneously in the matrix while the structure of the PI and MWNTs are stable in the preparation process. The composite films hold preferable thermal stability the same as the pure PI. The composite films exhibited good thermomechanical properties. The storage modulus increased significantly by increasing MWNT content and decreasing the enhancement of temperature. The films' glass transition temperature increased with enhancing of MWNTs frictions. The dielectric constants of the composites decrease with increasing frequency and increase sharply with the adding of MWNTs, which is favorable for practical use in anti-static materials and embedded capacitors.
期刊:
Journal of Chemical and Pharmaceutical Research,2013年5(11):802-810 ISSN:0975-7384
通讯作者:
Song, J.
作者机构:
[Song, Juanjuan] School of Chemical and Environmental Engineering, Hunan City University, Yiyang, Hunan, China
摘要:
As an absorbent dark tea residue can get rid of heavy metal ion effectually and do no harm to the environment. From the dynamic experiment on dark tea residue's absorption of Cr(VI), the absorption dynamic curve and absorption isothermal curve are obtained. The effects of pH value, initial concentration, dosage of residue, adsorption time and other factors on absorption are studied and the result shows that: when the pH value of the waste water is 2, the initial concentration is 100mg/L, the adsorption time is 60min, the dosage of dark tea residue is 1g, the maximum adsorption rate reaches 99.96%.The adsorption conforms with the Langmuir adsorption isotherm, it is a kind of monolayer adsorption, the adsorption kinetics curve conforms with pseudo-second-order equation. In the end discusses the development prospect of dark tea residue.
作者机构:
[陶美华; 梁法亮; 陈玉婵; 章卫民; 李冬利] Guangdong Open Laboratory of Applied Microbiology, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, Guangzhou 510070, China;[赵运林] Dark Tea Institute of Yiyang City, Department of Chemistry and Environment Engineering, Hunan City College, Yiyang 413000, China;[彭晓赟] Guangdong Open Laboratory of Applied Microbiology, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, Guangzhou 510070, China, Dark Tea Institute of Yiyang City, Department of Chemistry and Environment Engineering, Hunan City College, Yiyang 413000, China
通讯机构:
[Zhao, Y.-L.] D;Dark Tea Institute of Yiyang City, Department of Chemistry and Environment Engineering, Hunan City College, China
通讯机构:
[Long, Liping] H;Hunan City Univ, Coll Chem & Environm Engn, Yiyang 413000, Hunan, Peoples R China.
关键词:
Chemsensor;Hydrogen sulfide;CuS;Cell imaging
摘要:
A displacement method of detecting hydrogen sulfide in aqueous media based on complex L–Cu ensemble is developed. Once combined with Cu2+, complex L–Cu displayed high specificity for sulfide anion. Among the various anions, only sulfide anion induce the revival of fluoresecence of compound L, which is quenched by Cu2+, resulting in turn-on type sensing sulfide anion. Complex L–Cu exhibits a highly sensitive fluorescent response toward S2− by releasing compound L to give a remarkable change with 20-fold fluorescence intensity enhancement under 2 equivalent of S2− added in Tris–HCl/ DMF (20 mM, 6/4, v/v), and also exhibits a dynamic response range for S2− from 5×10−7 to 5×10−6 M, with a detection limit of 0.18 μM. In addition, the turn-on fluorescent change upon the addition of S2− is also applied in cell imaging.
摘要:
A fluorine-containing polyimide(FPI) was synthesized by reacting 4,4'-(hexafluoroisopropylidene) diphthalic anhydride (6FDA) with 2,2'-bis-(trifluoromethyl)-4,4'-diaminobiphenyl (TFDB). A series of polyimide composite films with various contents of nanosilica were prepared by an in situ polymerization technique. The obtained composite materials were analyzed with FTIR and the results showed that the amino groups were completely imidized. The morphology of the composites was characterized with SEM and the results indicated that the nanosilica particles integral dispersed but micro-aggregated in the fluoro-contained polyimide matrix if the nanosilica content excessed 10 wt %. The nanocomposite films were found to hold comparable thermal stability with the pure fluoro-contained polyimide film. The humidity absorption rate decreased with the increase of silica content. The dielectric constant of fluoro-contained polyimide/ nanosilica films decreased with increasing the frequency and exhibited an arch curve profile with its maximum value of less than 3, indicating the excellent dielectric property.
作者机构:
[王威燕; 王锋; 杨运泉] College of Chemical Engineering, Xiangtan University, Xiangtan 411105, China;[王锋] College of Chemical and Environmental Engineering, Hunan City University, Yiyang 413000, China
作者机构:
[Song, Juanjuan] Hunan City Univ, Sch Chem & Environm Engn, Yiyang 413000, Hunan, Peoples R China.;[Tu, Li] Hunan City Univ, Sch Informat Sci & Engn, Yiyang 413000, Hunan, Peoples R China.
会议名称:
2012 International Conference on Ecology,Waste Recycling,and Environment(ICEWE 2012)
会议时间:
2012-01-01
会议地点:
Macao,China
会议主办单位:
[Song, Juanjuan] Hunan City Univ, Sch Chem & Environm Engn, Yiyang 413000, Hunan, Peoples R China.^[Tu, Li] Hunan City Univ, Sch Informat Sci & Engn, Yiyang 413000, Hunan, Peoples R China.
会议论文集名称:
Advances in Biomedical Engineering
关键词:
modified diatomite;stibium;adsorption
摘要:
With increasing the degree of state environmental protection, the comprehensive treatment of waste water containing stibium has become a new subject in stibium industry.In this study,we modified diatomite with calcium carbonate,and adsorptived waste water containing stibium using these modified diatomite.Then we explored the quality of modified diatomite,initial concentration,initial pH value,temperature and adsorpting time on adsorption. The adsorption isotherm of stibium fits Langmuir equation.The result shows that the modified diatomite has good adsorption on waste water containing stibium.
作者机构:
[陈俊; 文杰斌; Chen, Jun; 李衡峰] School of Materials Science and Engineering, Central South University, Changsha 410083, China;[贺国文] Department of Chemistry and Environment Engineering, Hunan City University, Yiyang 413000, China
通讯机构:
[Li, H.] S;School of Materials Science and Engineering, Central South University, China