作者机构：
[Li, Zhihong; Zhou, Zhenhua] Hunan City Univ, Dept Phys Educ, Yiyang, Peoples R China.
会议名称：
2nd SREE Workshop on Medical Materials and Engineering, WMME 2012
会议时间：
SEP 15-16, 2012
会议地点：
Soc Resources Environm Engn, Hong Kong, PEOPLES R CHINA
会议主办单位：
Soc Resources Environm Engn
会议论文集名称：
Advances in Sciences and Engineering
关键词：
Neuropeptide Y (NPY);Calcitonin gene related peptide (CGRP);denervation;mobilization;Bone mineral density (BMD)
摘要：
This paper observed the changes of neuropeptide substance (calcitonin gene related peptide, CGRP; neuropeptide Y, NPY) level and its effects on bone mineral density, using the method of cutting off the nerves and fixing the hind legs. We found that: The content of NPY was highly related with BMD in denerved and immobilized groups. It can be observed as a key factor of Osteoporosis' formation. But the nerve integrity is a key for normal CGRP expression. Dynamic observation of changes of the CGRP content can forecast the formation and development of osteoporosis in a certain extent.
期刊：
Chinese Journal of Tissue Engineering Research,2009年13(33):6428-6432 ISSN：1673-8225
通讯作者：
Li, Z.-H.
作者机构：
[周振华; 李志宏] Department of Physical Education, Hunan City University, Yiyang 413000, Hunan Province, China;Department of Rehabilitation, Xiangnan University Affiliated Hospital, chenzhou 423000, Hunan Province, China;Li Zhi-hong, Master, Associate professor, Department of Physical Education, Hunan City University, Yiyang 413000, Hunan Province, China [email protected];[谢菊英] Department of Rehabilitation, Xiangnan University Affiliated Hospital, Chenzhou 423000, Hunan Province, China
通讯机构：
[Li, Z.-H.] D;Department of Physical Education, , Yiyang 413000, Hunan Province, China
期刊：
Chinese Journal of Tissue Engineering Research,2009年13(20):3933-3937 ISSN：1673-8225
通讯作者：
Li, Z.-H.
作者机构：
[李志宏; 周振华] Department of Physical Education, Hunan City University, Yiyang 413000, Hunan Province, China;Deparment of Rehabilitation, Affiliated Hospital of Xiangnan University, Chenzhou 423000, Hunan Province, China;It is believed that calcitonin-gene-related peptide (CGRP) can stimulate osteoblast proliferation, increase bone mass, and promote nerve regeneration. However, the change rule, effect and mechanism of CGRP on osteoporosis formation after different immobilization remain unclear.;To observe the effect, as well as possible mechanism of neuropeptide on bone mineral density (BMD) after denervation and immobilization.;The Randomized controlled animal experiment was completed in the Affiliated Hospital of Xiangnan University from September to November 2006.
通讯机构：
[Li, Z.-H.] D;Department of Physical Education, , Yiyang 413000, Hunan Province, China
