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A Novel Turn-on Fluorescent Probe for Highly Selective Detection of Phosphate Ion in Living Cell

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成果类型:
期刊论文
作者:
Zhang, Jin*;Wang, Si;Liu, Changhui;He, Guowen;Peng, Tianying
通讯作者:
Zhang, Jin
作者机构:
[Zhang, Jin; Liu, Changhui; Peng, Tianying; He, Guowen] Hunan City Univ, Sch Mat & Chem Engn, Yiyang 413000, Hunan, Peoples R China.
[Zhang, Jin; Wang, Si] Xiangtan Univ, Coll Chem, Key Lab Environm Friendly Chem & Applicat, Minist Educ, Xiangtan 411105, Hunan, Peoples R China.
通讯机构:
[Zhang, Jin] H
[Zhang, Jin] X
Hunan City Univ, Sch Mat & Chem Engn, Yiyang 413000, Hunan, Peoples R China.
Xiangtan Univ, Coll Chem, Key Lab Environm Friendly Chem & Applicat, Minist Educ, Xiangtan 411105, Hunan, Peoples R China.
语种:
英文
关键词:
analytical methods;sensors;2-(2-hydroxyphenyl)benzothiazole;cell recognition;pi detection
期刊:
中国化学
ISSN:
1001-604X
年:
2018
卷:
36
期:
12
页码:
1179-1181
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21675042]; Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2017JJ2018]
机构署名:
本校为第一且通讯机构
摘要:
A novel fluorescent probe was synthesized and studied. Fluorescent probe 1 undergoes a unique Pi induced hydrolytic reaction in DMSO- HEPES at physiological pH that produces a colorimetric change associated with a 76 nm red-shift in the UV-vis absorption maximum and up to a 210-fold enhancement in the fluorescence intensity. It has successfully been used to stain and record microscopy images of HeLa cells. Moreover, the mechanistic proposal that these spectroscopic changes are associated with the reaction of Pi and probe 1 to form 2-(2-hydroxyp...

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