A causal effects of neutrophil extracellular traps and its biomarkers on acute respiratory distress syndrome: a two-sample Mendelian randomization study
The present work was supported by the “Star of Jiaotong University” program of Shanghai Jiao Tong University Medical and Industrial Cross Research Fund Project (No. YG2019ZDB08).
机构署名：
本校为其他机构
院系归属：
机械与电气工程学院
摘要：
Previous studies have indicated an association between neutrophil extracellular traps (NETs) and acute respiratory distress syndrome (ARDS). This study aimed to investigate the potential causal effects of NETs and NETs-related biomarkers on ARDS or vice-versa. A two-sample Mendelian randomization (MR) utilizing genome-wide association studies (GWAS) data was employed to analyze the causality. The primary analysis was conducted using inverse-variance weighted (IVW) methods; weighted median, MR-Egger, and weighted model methods were used to valid...
