Isolation, bioactivity and molecular docking of stilbene acetylcholinesterase inhibitors from Arundina graminifolia (D. Don) Hochr.

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成果类型：

期刊论文

作者：

Zhang, Xingyu*;Chen, Weichi;Liu, Meifeng

通讯作者：

Zhang, Xingyu;Liu, MF

作者机构：

[Zhang, Xingyu] Hunan City Univ, Sch Mat & Chem Engn, Hunan Prov Key Lab Dark Tea & Jinhua, Yiyang 413000, Peoples R China.

[Liu, MF; Chen, Weichi; Liu, Meifeng; Zhang, Xingyu] South China Univ Technol, Sch Chem & Chem Engn, Key Lab Funct Mol Engn Guangdong Prov, Guangzhou 510640, Peoples R China.

通讯机构：

[Liu, MF ; Zhang, XY] S

South China Univ Technol, Sch Chem & Chem Engn, Key Lab Funct Mol Engn Guangdong Prov, Guangzhou 510640, Peoples R China.

语种：

英文

关键词：

A. graminifolia;Acetylcholinesterase;Ephemeranthoquinone;Structure-activity

期刊：

Journal of Molecular Structure

ISSN：

0022-2860

年：

2025

卷：

1332

页码：

141745

DOI：

10.1016/j.molstruc.2025.141745

基金类别：

CRediT authorship contribution statement Xingyu Zhang: Writing – review & editing, Writing – original draft, Project administration, Methodology, Investigation. Weichi Chen: Writing – review & editing, Software. Meifeng Liu: Writing – review & editing, Project administration, acquisition.

机构署名：

本校为第一机构

摘要：

Twelve stilbenes were isolated and characterized from Arundina graminifolia (D. Don) Hochr ( A. graminifolia. ), including arundin (1) , isoarundinin II (2) , batatasin III (3) , blestriarene A (4) , densiflorol B (5) , shancidin (6) , coeloin (7) , ephemeranthoquinone (8) , isoshancidin (9) , lusianthridin (10) , orchinol (11) , and arundinan (12) . Notably, compounds 1 and 2 are reported here for the first time from this species, thereby expanding the chemical profile of A. graminifolia . Among these, compounds 4, 7 , and 8 exhibited signific...

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Isolation, bioactivity and molecular docking of stilbene acetylcholinesterase inhibitors from Arundina graminifolia (D. Don) Hochr.

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