期刊论文

中文

中华生物医学工程杂志

1674-1927

2022

28

04

374-380

10.3760/cma.j.cn115668-20210706-00163

本校为其他机构

目的:观察面罩比例辅助通气（PAV）时气流阻塞严重程度对人机同步性和呼吸做功的影响。方法:使用ASL 5000机械肺模拟器模拟慢性阻塞性肺疾病（COPD）患者，系统顺应性（C rs）为50.0 ml/cmH 2O[弹性阻力（E rs）为20.0 cmH 2O/L]、气道阻力（R aw）分别为5.0、10.0和20.0 cmH 2O·L -1·s -1。吸气时间为1.6 s，呼吸频率为15次/min。Respironics V60呼吸机在压力支持通气（PSV）时输出潮气量（V T）为7.0 ml/kg，PAV通气时流量辅助（FA）设置为5.0、10.0和20.0 cmH 2O·L -1·s -1，容量辅助（VA）为20.0~40.0 cmH 2O/L，辅助比例为50%。呼气末正压（PEEP）为5.0 cmH 2O，后备通气...

Objective:To evaluate the impact of airflow obstruction severity on patient-ventilator synchrony and work of breathing (WOB) during facial mask proportional assist ventilation (PAV) .Methods:ASL5000 lung simulator was used to simulate the lung mechanics in patients with chronic obstructive pulmonary disease (COPD) , set with a respiratory system compliance (C rs) of 50.0 ml/cmH 2O, a respiratory system elastance (E rs) of 20.0 cmH 2O/L, airway resistance (R aw) of 5.0, 10.0 or 20.0 cmH 2O·L -1·s -1, inspiratory time (T I) of 1.6 sec,...