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The theoretical 3D structure of Bacillus thuringiensis Cry5Ba

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成果类型:
期刊论文
作者:
Xia, Li-Qiu*;Zhao, Xin-Min;Ding, Xue-Zhi;Wang, Fa-Xiang;Sun, Yun-Jun
通讯作者:
Xia, Li-Qiu
作者机构:
[Ding, Xue-Zhi; Xia, Li-Qiu; Sun, Yun-Jun; Wang, Fa-Xiang] Hunan Normal Univ, Coll Life Sci, Key Lab Microbial Mol Biol Hunan Prov, Changsha 410081, Peoples R China.
[Zhao, Xin-Min] Hunan City Univ, Dept Environm Chem & Engn, Yiyang 413000, Peoples R China.
通讯机构:
[Xia, Li-Qiu] H
Hunan Normal Univ, Coll Life Sci, Key Lab Microbial Mol Biol Hunan Prov, Changsha 410081, Peoples R China.
语种:
英文
关键词:
Three-dimensional structure;Homology modeling;Cry5Ba;Bacillus thuringiensis
期刊:
Journal of Molecular Modeling
ISSN:
1610-2940
年:
2008
卷:
14
期:
9
页码:
843-848
机构署名:
本校为其他机构
院系归属:
材料与化学工程学院
摘要:
Cry5Ba is a delta-endotoxin produced by Bacillus thuringiensis PS86A1 NRRL B-18900. It is active against nematodes and has great potential for nematode control. Here, we predict the first theoretical model of the three-dimensional (3D) structure of a Cry5Ba toxin by homology modeling on the structure of the Cry1Aa toxin, which is specific to Lepidopteran insects. Cry5Ba resembles the previously reported Cry1Aa toxin structure in that they share a common 3D structure with three domains, but there are some distinctions, with the main differences being located in the loops of domain I. Cry5Ba exh...

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