版权说明 帮助中心
首页 > 成果 > 详情

Reversible molecular switching of molecular beacon: controlling DNA hybridization kinetics and thermodynamics using mercury(ii) ions.

SCI-EMedline
WOS被引频次:69
认领
导出
Link by DOI
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
Yang, Ronghua;Jin, Jianyu;Long, Liping;Wang, Yongxiang;Wang, Hao;Tan, Weihong
通讯作者:
Yang, RH
作者机构:
[Yang, Ronghua; Long, Liping; Tan, Weihong] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China.
[Yang, Ronghua; Long, Liping; Tan, Weihong] Hunan Univ, Ctr Biomed Engn, Coll Chem & Chem Engn, Changsha 410082, Hunan, Peoples R China.
[Yang, Ronghua; Jin, Jianyu; Wang, Yongxiang; Wang, Hao] Peking Univ, Coll Chem & Mol Engn, Beijing 100871, Peoples R China.
[Long, Liping] Hunan City Univ, Dept Chem & Environm Engn, Yiyang 413500, Hunan, Peoples R China.
[Tan, Weihong] Univ Florida, Ctr Res Bio Nano Interface, Dept Chem, Gainesville, FL 32611 USA.
通讯机构:
[Yang, RH] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China.
语种:
英文
期刊:
Chemical communications (Cambridge, England)
ISSN:
1359-7345
年:
2009
期:
3
页码:
322-324
文献类别:
WOS:Article
所属学科:
ESI学科类别:化学;WOS学科类别:Chemistry, Multidisciplinary
入藏号:
WOS:000262176800016;PMID:19209316
基金类别:
National Outstanding Youth Science Foundation of China [20 525 518]; National Natural Foundation of China [20 775 005]; NSF; NIH
机构署名:
本校为其他机构
院系归属:
信息与电子工程学院
材料与化学工程学院
摘要:
We report that the hydrogen-bonding pattern in a molecular beacon can be replaced by metal-dependent pairs of Hg(2+) and DNA thymine ( T) bases. A molecular beacon based on T-Hg(2+)-T exhibits a lower background signal and higher thermostability than regular molecular beacons.
参考文献:
Bourdoncle A, 2006, J AM CHEM SOC, V128, P11094, DOI 10.1021/ja0608040
Braasch DA, 2001, CHEM BIOL, V8, P1, DOI 10.1016/S1074-5521(00)00058-2
Fang XH, 2002, CELL BIOCHEM BIOPHYS, V37, P71, DOI 10.1385/CBB:37:2:071
Feldman SH, 2007, LAB ANIMAL, V36, P43, DOI 10.1038/laban1007-43
Gao XY, 2008, J AM CHEM SOC, V130, P9190, DOI 10.1021/ja801793k

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com