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Amperometric immunosensor for probing complement III (C3) based on immobilizing C3 antibody to a nano-Au monolayer supported by sol–gel-derived carbon ceramic electrode

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成果类型:
期刊论文
作者:
Lei, CX;Yang, Y;Wang, H;Shen, GL;Yu, RQ*
通讯作者:
Yu, RQ
作者机构:
[Yu, RQ] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Peoples R China.
Hunan City Univ, Dept Environm Chem & Engn, Yiyang 413049, Peoples R China.
通讯机构:
[Yu, RQ] H
Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Peoples R China.
语种:
英文
关键词:
Amperometric immunosensor;Carbon ceramic electrode;Complement III;Nano-Au monolayer
期刊:
Analytica Chimica Acta
ISSN:
0003-2670
年:
2004
卷:
513
期:
2
页码:
379-384
基金类别:
Financial support from the National Natural Science Foundation of China (Grant Nos. 29975006, 20075006) is gratefully acknowledged.
机构署名:
本校为其他机构
院系归属:
材料与化学工程学院
摘要:
An electrochemical immunosensor based on nano-size particulate gold (nano-Au) monolayer as sensing interface has been developed for probing complement III (C3). The thiol functional group-derived carbon ceramic electrode (CCE) was firstly constructed using (3-mercaptopropyl) trimethoxy silane (MPTMOS) as sol-gel monomer. The stable nano-Au monolayer was obtained resulting from covalent combination between nano-Au and thiol group on the surface of CCE. The nano-Au monolayer formed was utilized as a sensing platform for the immobilization of C3 a...

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