Taking the per capita GDP as the index, using the method of traditional statistics and ESDA, this paper analyzed the temporal and spatial characteristics of the Midstream of the Yangtze River Economic Area' s county economy differences from 2001 to 2010.Then it preliminarily explored the impact factors by multivariate linear regression analysis method. The results show that: (1) The absolute difference of economic zone enlarges constantly, but the relative difference has a changing trend of "M"; The internal differences of Wuhan City Circ...