期刊论文

The measurement of respiratory mechanics with new dynamic approach during noninvasive bi-level positive pressure ventilation: a bench study

中文

中国呼吸与危重监护杂志

1671-6205

2019

18

6

537-542

10.7507/1671-6205.201901070

科技部国家重点研发计划“重大慢性非传染性疾病防控研究”重点专项项目(2018YFC1313600) 上海交通大学“交大之星”医工交叉研究基金(YG2019ZDB08)。

本校为其他机构

目的观察经口鼻面罩实施压力支持通气(PSV)时不同压力支持(PS)水平对肺力学模型呼吸力学特性参数测算准确性的影响。方法使用ASL5000肺模拟器模拟慢性阻塞性肺疾病患者,设置系统顺应性(C_(rs))为50 mL/cm H_2O,气道阻力(R_(aw))为20 cm H_2O/(L·s),吸气时间为1.6 s,呼吸频率为15次/min。Respironics V60呼吸机以S/T模式运行,呼气末正压为5 cm H_2O,PS水平分别为5、10、15、20和25 cm H_2O,后备通气频率为10次/min。收集在系统泄漏量为25~28 L/min时的通气参数变化并采用新型动态法测算C_(rs)以及吸气和呼气阻力(R_(insp)和R_(exp))。结果PS为5、10和20 cm H_2O时,潮气量(V_T)分别为(281.45±4....

Objective To evaluate the accuracy of the new dynamic approach in the measurement of respiratory mechanics with different pressure support (PS) level during pressure support ventilation (PSV) via oral-nasal mask. Methods The Respironics V60 ventilator was connected to a ASL5000 lung simulator, which simulate lung mechanics in patients with chronic obstructive pulmonary disease [system compliance (C_(rs))=50 mL/cm H_2O, airway resistance (R_(aw))=20 cm H_2O/(L·s), inspiratory time (TI)=1.6 s, breathing rate=15 beats per minute]. PSV were applie...